Description of the RI

The Hungarian Centre for Genomics and Bioinformatics RI provides an integrated, streamlined and expertly supported next generation sequencing (NGS) based services that encompass experimental design, sample preparation, sequencing, data analysis and interpretation. An expert team of laboratory scientists and bioinformaticians is available to consult and collaborate at every step of the research and diagnostic projects. They work closely together to develop optimized experimental strategies to ensure the appropriate application, technology and data analysis tools are applied to address both standard and unique questions.

The Centre provides the most cost-efficient integrated service portfolio for academic and industrial partners working on the fields of healthcare, agriculture and food safety. Currently, the RI has one of the highest sequencing and computational capacities in Hungary and Eastern Europe, including all the major sequencing platforms and high-performance computing (HPC) resources.

The RI puts a strong emphasis on establishing collaborations and working together with the national nodes of European research infrastructures including ELIXIR, ECRIN and BBMRI.

Activities and Services

The Hungarian Centre for Genomics and Bioinformatics offers a broad range of NGS services on short-read sequencing Illumina platforms (NovaSeq, NextSeq, MiSeq, MiniSeq and iSeq) and long-read sequencing Oxford Nanopore technology (MinION). The application areas consist of genome, transcriptome, epigenome and metagenome sequencing. The RI’s end-to-end services include advice on study design, library preparation strategies for various sample types, and the appropriate sequencing application with the suitable bioinformatics data analysis methods.

In addition to engaging in research collaborations with academic partners, the RI works together with health and agriculture biotech companies to develop and implement new innovative solutions for their needs. The Centre offers diagnostics support for clinical institutes with its 1) whole exome and genome sequencing applications for rare (inherited) diseases, 2) targeted sequencing solutions for precision oncology, and 3) pathogen (virus and bacteria) point-of-care testing.