Description of the RI

The Research Infrastructure at the Institute of Chemistry, University of Debrecen is an inter- and multi-disciplinary core-center that supports research activities in diverse areas from chemistry, biology, biochemistry, medicine and material sciences to plastic industry. The state-of-the-art instruments installed in the Research Infrastructure extend the scope of academic and innovation research activities of the Institute of Chemistry and provide indispensable links between academic and industrial research.

The pharmaceutical industry and R&D (e.g. TEVA, BorsodChem, GLYCOM, Richter) have established a solid and fruitful relationship with our research facility.

Activities and Services

The Bruker Avance NEO 700 MHz NMR spectrometer equipped with Prodigy TCI cryoprobe offers outstanding sensitivity and resolution, supporting research activities in diverse areas. The Research Infrastructure with the three other spectrometers (Bruker 360, 400, 500) offers a wide range of high resolution, multinuclear and multidimensional NMR measurements for structure determination and dynamics study of carbohydrates, peptides, proteins and other synthetic and natural products. The research team has special expertise in method development for sensitive and reliable measurement of important NMR parameters. The high resolution and high sensitivity mass spectrometers (Bruker maXis II ESI-QTOF-MS and Bruker Autoflex Speed MALDI-TOF-TOF MS) allow the determination of accurate molecular masses and structures of small to large (bio) molecules. The Bruker D8 Venture X-ray diffractometer allows the determination of the crystal and molecular structures of small molecules, metal complexes or even proteins.

Additional essential elements of the RI:

• Infrastructure for designing, constructing and applying microfluidic chips (lab-on-a-chip systems).
• Capillary electrophoresis systems for proteomics, environmental and pharmaceutical analytic applications.
• QTOF mass spectrometer equipped with ESI, APPI, APCI, DART ion sources.
• Chromatographic systems, optical spectroscopy techniques, mechanical analyzers (DMA)